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Oral problems - Mouth, Tooth and Dental Care
Dental lesions in CRF cat
Gingivitis, antibiotics
Oral inflammatory disorders
Lymphocytic/plasmocytic
gingivitis
Tiny black spots on teeth
Severe Gingivitis in Kitten
Loss of canine tooth
Teeth, gums and FIV
Gingivitis plus
also see Feline Leukemia
also see FIV
also see Respiratory Problems
Dental lesions
in CRF cat
Question: My 17 year old siamese was diagnosed with chronic renal
failure a year ago. Her teeth are not in
good shape and I am worried that this could worsen her condition.
The vet told me she has a
reabsorbtion lesion that is painful. When my cat yawned today
I saw a black spot on her back
tooth that looks like it could be a cavity. One vet told me
that putting my cat under anesthesia to
pull/clean teeth would be too risky; her kidneys wouldn't be
able to filter the anestethia and she
could die. Another vet scolded me and said that she needed
the tooth pulled b/c the lesion is
painful. I am really worried that my cat is in pain but
I'm afraid to put her under to get her teeth
pulled. I would appreciate your advice on this matter.
My cat's latest blood tests are: BUN 40.3,
Creatnine 3.25
Thank you,
Cathy
Answer: Cathy-
I think that dental lesions are painful enough that overall health improves
when they are dealt with. So
I almost always want to pursue anesthesia. However, there is some increase
in risk when kidney
disease is present and it is important to realize this and to compensate
for it. The major risk to cats
with kidney disease is low blood pressure occurring for a significant
length of time during an
anesthetic procedure. Giving fluids intravenously during the procedure
helps to reduce this risk. In
some instances a procedure may be short enough that it seems unnecessary
to do this, but it is a
good precaution for most anesthetic procedures in cats with kidney
failure. It is also a good idea to
try to rule out high blood pressure prior to the time that the anesthetic
is given. Many cats with kidney
failure have high blood pressure because of the effects of the kidney
failure on the blood pressure
regulatory system. It is good to consider this possibility when planning
which anesthetics to use. With
care, I think that anesthesia in patients with kidney failure is nearly
as safe as in patients without this
problem but it is necessary to consider it when planning the anesthetic
procedure.
There is a small risk of death with anesthetic procedures but the increase
in the quality of life for so
many patients outweighs this risk, in my opinion. Some people view
death as such a prohibitive risk
that they are willing to tolerate a lot of discomfort to avoid any
anesthetic risk. This is a value
judgment that has to be made by each person making this decision and
so both vets are entitled to
their opinion. While I favor being willing to take a small risk
to increase the quality of a patient's life,
it is just my personal opinion. I try to present both sides and let
my clients make the decision based
on their view of the benefits and risks. It is just really important
to remember that patients with dental
disease are often in pain, so there is often a great benefit to dental
care, even if it does require
anesthesia. Sometimes, an increase in drinking and eating after dental
care causes significant
improvements in illnesses like kidney or liver failure, too.
Mike Richards, DVM
6/5/2001
Gingivitis, antibiotics
Question: Dr Mike,
I had my 9 1/2 year old cats teeth cleaned a month ago. She had
severe gingivitis. She is now getting the bad
breath again. She also sneezes everyday. Is she going
to need her teeth cleaned every month? Could she
have other problems making her prone to the gingivitis? Is it
a good idea to have a blood test done on both
cats?
Answer: There is pretty good evidence now that periodic use of
clindamycin, an antibiotic, can slow the
progression of periodontal disease in cats, making it possible to go
longer between dental cleansings
in patients who develop recurrent periodontal disease quickly. This
may be worth considering.
Giving the medication the first seven to ten days of each month is
one example of a periodic schedule
that seems to help. You might think about this for your older cat if
your vet thinks it might help, too.
There are problems that cause increases in the incidence of periodontal
disease, such as kidney
disease, feline immunodeficiency virus, food allergies and immune mediated
disorders. Blood tests
can help rule out some of these causes. It is usually possible to draw
blood without sedation but
there are some exceptions.
I hope that things have improved some since you wrote.
Mike Richards, DVM
2/3/2001
Oral inflammatory
disorders
Question: Hi Dr Mike,,
Thank you for getting back to me. My Cat Sam was having a problem with
his
throat and my vet said that he has stomatitis. His gums are not bad
but his
throat is very sore. My Vet gave him a depo medrol shot about 3-4 weeks
ago
and a few days after the shot his eye got really infected looking.
I
took Sam back to the vet and was told to put vetropolycin in his eye.
After apx 5
days I took him back in and was given terramycin, I used that for 7
or 8 days and
his eye still was not better. Finally my vet tested for herpes. We
should
have the results back tues or weds. In the mean time Sams eye looks
better
but his throat is hurting him again. My vet said to just try and get
him to eat baby
food or something that won't hurt his throat until he gets the results
of the herpes test. Is there any advice that you can give my vet??
Sandy-
Answer: I think that the best help that I can give you at this
time is a list of
the possible oral inflammatory disorders and some of the treatments
that
have been advocated for individual conditions. It is important, when
possible, to identify the underlying cause of problems affecting the
oral
cavity that appear to be chronic because they often are very difficult
to
resolve and may require long term maintenance therapy. It is worth
having a
biopsy sample taken of the sores, considering oral X-rays and a dietary
trial to eliminate food allergies, as well as other diagnostic testing
if
there is not a good response to initial treatment attempts.
One thing in your note did stand out for me. If you really believe that
there is soreness in Sam's throat, rather than around his teeth, there
is a
higher probability that you are dealing with plasma cell stomatitis
rather
than some of the other things in the list that follows.
These are the most common of the oral inflammatory conditions seen in
cats:
feline herpes virus or calcivirus infection
these will usually
heal on their own without treatment but there
can be long term problems due to calicivirus
feline leukemia virus (FeLV)
it is often necessary
to treat for secondary infections when FeLV
is present some people feel that treatment with interferon is helpful
for
FeLV infections
feline immunodeficiency virus (FIV)
FIV has a strong tendency
to cause gingivitis and it is a good
idea to test for this virus when persistent gingivitis is a problem
AZT is the most commonly
recommended medication for FIV infections
but work is being done on developing multiple drug treatments
at the
current time it is somewhat controversial to use corticosteroids in
FIV
patients but it seems to help some of them
eosinophilic granuloma complex
this is an immune
mediated disorder associated with flea allergies
and food allergies but it can occur for no apparent reason and
may also
occur with atopy (inhalant allergies
corticosteroids are
the most consistently successful treatment for
this condition but it has also been treated with megestrol acetate
(Ovaban Rx) and may respond to hypoallergenic diets, flea control or
allergy injections (hyposensitization)
there are lots of
other treatments that have helped in some cases
lymphocytic/plasmacytic gingivitis or plasma cell stomatitis (plus
other
variations of these names)
this condition may
be related to calicivirus infection but seems
to be an immune mediated disorder in most cats. High gamma globulin
levels in the blood stream are supportive of a diagnosis of this
condition. It is postulated that some cats are sensitized to their
own teeth and removal of the teeth behind the canines (cuspids)
will
cure this condition in approximately 60% of cats.
Oral corticosteroids,
teeth cleaning on a routine basis, removal
of teeth with odontoclastic lesions (holes in the enamel similar to
cavities), other immunosuppressive medications (cyclosporin is
currently
being used) and sometimes antibiotic therapy are the standard
treatments and are successful in a large percentage
of cats.
A small percentage
(<20%) of cats seem to respond to bovine
lactoferrin administration for this problem. It is pretty safe to
use this so we have tried it several times and our results seem to
match the 20% figure
this condition tends
to cause signs that clients think of as a
sore throat, so I would be most concerned that this is the problem
for Sam but the best way to try to get a diagnosis is by biopsy an
affected area of tissue. This can be done at the time of teeth cleaning.
This can be a very
frustrating condition.
Ulcerative necrotizing stomatitis (this is called trench mouth in humans)
Examining a smear
made from the inflamed area might reveal a lot
of spirochete bacteria, which are the cause of this problem.
Bacterial
cultures can reveal the problem and it is discernible by biopsy, or
at least we have had a biopsy sample come back with this diagnosis,
so we assume it is.
Antibiotic therapy
for at least 3 to 4 weeks is necessary to
control this problem
Oral cancers are the last group of problems that is somewhat common
and can
lead to the signs that you are seeing.
This possibility
is another reason to consider biopsy of the
affected area. I have seen several references that state that it is
not possible to differentiate eosinophilic granuloma lesions from oral
cancers, even for experienced observers.
The appearance of the eye lesion after administration of a corticosteroid
is very suspicious for herpes virus infection, even if herpes virus
is not
found in testing. Right at this time, there isn't a completely reliable
lab
test for herpes virus. Herpes virus eye lesions often have infiltration
of
blood vessels in a pattern reminiscent of a lightening bolt, so that
may
help in differentiating what is going on. If there was a pre-existing
eye
infection or scratch on the eye at the time of the cortisone injection
it
could conceivably lead to a corneal ulcer, so herpes virus is not the
only
possibility, just the most likely one.
It can be frustrating to work through the possible problems while your
cat
feels bad due to the existing sores. The quickest way to an answer
is
probably to allow a good dental cleaning, with biopsies taken of several
sites that are inflamed. Then while awaiting the pathlogist's report
consider trying a hypoallergenic diet, such as Hill's z/d diet or a
limited
antigen diet like Hill's d/d or Innovative Diets foods (they make several).
We often use antibiotics as the only medical therapy for a few days
early
in the effort to diagnose these conditions. If there is great improvement
in a few days, we keep going with them for three to four weeks. Once
in a
while this resolves a problem. More often, there isn't much improvement
within a week so we go ahead and go to corticosteroids to try to make
our
patients comfortable.
There is a tendency to use laser treatments for the plasma cell stomatitis
problems at the present time. This seems to provide temporary relief
but it
doesn't resolve the underlying problem and my impression is that return
of
the problem quickly is more common than a cure with laser therapy.
I hope this helps to start out. If this raises additional questions
please
feel free to send them.
Mike Richards, DVM
1/17/2001
Lymphocytic/plasmocytic
gingivitis
Question: My five-year-old Cornish Rex has had mouth problems.
Last week I finally
bit the bullet and had him sedated (he has a heart murmur) and a biopsy
done; the diagnosis was what the vet expected, which is chronic
plasmocytic gingivitis. Right now we're trying 1 cc daily of oral
prednisone until he gets better, then it will be 1 cc every other day.
After a week he still seems to have pain when he eats. (It's not the
teeth, which, the dentist said, "looked pretty good.") He tested
negative
for FIV and FeLV last March but does go outside on a "Saturday afternoon
in good weather" kind of basis. However, the problem was beginning
to
show up as early as last January so I doubt it's FIV related.
But it
COULD be.
Are there any other treatments that might be effective? What CAUSES
this,
anyway?
Answer: Stephanie-
If corticosteroids don't work alone for lymphocytic/plasmocytic gingivitis
problems in cats, sometimes adding azathioprine (Imuran Rx) or another
immunosuppressive agent works. I haven't tried any other ones and have
had
some cats that the combination didn't work in.
Removal of all of the teeth except the four big canines and the incisors
is
an effective treatment for this condition in many cats. It has to be
done
correctly, though. Leaving any root fragments can leave problem areas.
This
sounds like a radical option but it works pretty well.
There was an article in the AVMA research journal in 1996 on something
called bovine lactoferrin that suggested it worked well for this problem.
It was in the October issue and was written by Sato et al. I think
I can
find a dosage if necessary. It has to be applied topically, which seems
like it could be a problem in some cats. In addition, there is a CO2
laser
treatment for this condition that is reported to work in some cats,
too. I
don't know much about this, either -- but it is still an option to
look
into if cortisones don't work.
So there are options. We have only used the corticosteroids,
corticosteroid/azathioprine combination and extraction and so far have
been
able to resolve most cases of this problem. I don't think I'd hesitate
to
try the other options if they are more attractive to you than tooth
extraction, though.
Hope you have success with cortisones alone.
Mike Richards, DVM
10/1/99
Tiny black spots
on teeth
Question: Dear Dr. Richards,
I am a subscriber and have another question about Shadow (my Snowshoe
kitty with the quivering eyes)...his gingivitis continues to be a
problem that's still being worked on but very recently he's gotten
very
tiny (like a pin prick) black spots on some of his teeth and not near
the gums. He's scheduled for a teeth cleaning very soon.
Do you have
any ideas? Thanks very much, Leslie & Shadow
P.S. He eats Waltham's pHformula dry food and a tiny bit of canned
food.
Answer: Leslie-
I can't help with this question. Your vet will hopefully be able to
give
you information after examining and cleaning the teeth. There is some
chance that these are odontoclastic resorption lesions but they usually
occur near the gumline. Not always, though. Some sort of staining of
the
enamel seems possible, too. I don't know what would stain the enamel
in
small spots like you describe, though. I wish I could help some
with this
but you're going to have to rely on your vet for this one.
Mike Richards, DVM
1/31/2000
Severe gingivitis
in kitten
Q: I have read alot of stuff on the internet, but
I just would like to hear what you have to say on this as well. I got my
kitten in April, she was 4 months old at that time. Her breath seemed a
little weird but it would come and go. She eats Iams Eukabana Chicken and
Rice (dry). The other day she was biting at my fingers and I noticed that
her gums were swollen and red so we went to the Vet today. The vet said
it is not due to tartar buildup so she would have to do a biopsy next week
and put her under to do it to find out the cause. What is the usual course
on these things and is there anything I should be worried about. She is
a Birman, are they prone to such an illness. Anyway I am worried alot and
thought maybe you could help. Thanks. Susan
A: Susan- There are several possible problems when
young cats have severe gingivitis. One of these, often referred to as "juvenile
gingivitis" has not been well characterized. Presently I think the major
theory is that it is the result of chronic calicivirus infection but am
not absolutely certain that a definitive cause has not been found. This
type of gingivitis seems to respond to persistent teeth cleaning (often
takes several closely spaced cleanings) and treatment with fluoride or
chlorhexidine (or both) may also be helpful. Plasmacytic/lymphocytic gingivitis
can be diagnosed by biopsy. This sometimes responds to anti-inflammatory
medications. It is more common in more mature cats and sometimes requires
removal of the teeth where the gums are inflamed. Feline immunodeficiency
virus is often associated with gingivitis. Feline leukemia may occasionally
play a role in it. Kidney disease may be present but usually there are
a lot of other problems in this case (poor growth, drinking and urinating
a lot).
X-rays to look for bone resorbption can help sort through the problems
affecting the teeth (bone loss occurs in juvenile gingivitis). Teeth cleaning
can help determine what is going on. Since this usually takes anesthetic
doing a biopsy at the same time seems reasonable to me.
Good luck with this.
Mike Richards, DVM
Lost canine tooth
Q: I panicked this morning when I saw my 12-year
old cat, Muffy, meow and noticed that her upper left canine tooth was missing!!
I tried to look in her mouth and saw that where the tooth had been didn't
look red or infected. How could a cat lose a tooth like that without showing
signs of distress. She had an upper respiratory infection in February and
refused to eat for about 4 days. On the advice of my vet I kept her hydrated
with chicken broth and tried everything to get her to eat. Then I took
her to the vet for a vitamin injection. It worked and within 12 hours she
was eating everything she get a hold of. Her weight did drop some during
the illness but her appetite continued to be strong and the vet suggested
putting her on the Hill's Health Blend Geriatric formula. (she was on c/d
but never would eat it again). She didn't like the canned version of the
Geriatric but liked the dry. It is lower in fat and never thought too much
about her weight not coming back up. She has had a continuously watering
eye and had been checked twice but the vet said it might be a clogged tear
duct or a result of the herpes virus that sweep throug the house in February.
She was treated with an eye ointment but it never stayed cleared up. The
only time that she didn't have the watering eye was when she had the respiratory
infection which seems strange. Could this watering eye have been a signal
that a tooth was infected? I can't believe that we all missed it. She seemed
very healthy. Very energetic and affectionate. Her urine and stool is normal
and her fur is shiny and free from dandruff. I have been giving her a natural
canned food for the last month (Pet Guard brand) and she loves it. After
the respiratory infection, the only food she would eat was Friskies Senior.
(I never felt comfortable giving her a supermarket brand food) Since she
refused all the canned food from Hill's, I tried the Pet Guard. I don't
know when the tooth came out but it seemed to have healed. She is still
able to eat dry food but should I continue to let her eat the dry with
this tooth missing? I feel so bad that she lost a major tooth and no one
could see the problem ahead of time. Do these things happen? Any information
you can provide would be appreciated. Thank You. Lou.
A: Lou- The canine teeth have extensive roots and
this is where damage to these teeth often occurs. There may be little to
no sign of problem above the gum line. Periodontal disease is one cause
of losing canine teeth but it usually advanced when they finally come out
on their own. Her other teeth should show signs of this condition if it
is present. Odontoclastic lesions (cervical neck lesions) are a condition
that is seen in cats in which cavities form just at or just below the gumline.
These will eventually weaken the tooth to the point that it comes out.
This would have to have been going on a while too, but these are harder
to see. It is uncommon for this to happen in just one tooth so it may be
a good idea to check for these lesions in her other teeth. Often a small
reddened area (like a flap) is visible at the base of the tooth where it
meets the gumline when one of these lesions is present. It seems inconceivable
that these cavities wouldn't hurt but many cats do not show any obvious
signs of distress.
Odontoclastic resorptive lesions sometimes respond to "filling" using
glass isomers or other methods but many of them continue developing despite
this sort of treatment. If this is an option you would like to pursue it
would be important to find a vet with at least an interest in dentistry
or preferably a board certified veterinary dental specialist. Since the
success rate of treatment long term is reported to be about 33% many vets
just recommend removal of affected teeth, especially if visible discomfort
is present.
Mike Richards, DVM
Teeth, gums and FIV
Q: Hi, Dr. Mike. About a week ago I took my one
year old male oriental/tabby to my vet to get his booster ect. in preparation
for "tutoring". Dewberry is the offspring of my girlfriends female oriental
tabby and my 2yr old male tabby. The litter was quite large, she had nine
kittens, seven of which survived, which we thought was quite remarkable
for a cat that weighs less than ten pounds having her first litter. Dewberry
was the runt of the litter, he had to be fed at times with a dropper. When
he was about 2 months old he developed an infection in his back legs (about
two days apart) we immediately took him to the emergency, and as it was
only one leg, the emergency attentant thought it may have been a strain
from aggressive kitten play. They recommended keeping him in the carrier
for a couple of days to slow him down to allow it to heal. When we noticed
his other leg was swelling we brought him back and they gave him an antibiotic
(milky texture). The swelling went down in a couple of days. He has gone
on to be the largest of all the kittens (much longer and taller). He is
a very well mannered, happy little boy, who has no lack of energy and likes
to get into everything. His appitite is good, his eyes are clear and bright,
his coat is shiney, (although he gets the occasional zit like both his
parents) and his stool is solid. On his last visit to the doctor, while
getting his booster, the vet noticed some reddness in his gums around his
K9s. (I have a 4 year old DSH who has bad tarter on his back teeth so I've
recently changed thier food from Whiskas to Standard Choice, quite noticably
crunchier). When the vet noticed the gums he suggested the possibility
of FIV, even though he thought he was healthy in every other way (we are
in touch with the owners of his brothers and sisters, and they are all
healthy). He has never been out side as all our cats are indoor cats.He
still has to wait at least another week or two before he can get neutered.
The health of our cats is very important to us and I'm wondering if I'm
just overreacting, or if our concern is justified and we should get him
to the vet immediately. Thank you for your attention to this matter (sorry
for the length of this letter).
A: . Feline immunodeficiency virus (FIV) infection
is associated with gum disease and calcivirus infection can also cause
redness of the gums around the teeth. Sometimes this seems to be just from
teething (especially if it occurs when they are teething and goes away
when the permanent teeth are in). You might want to consider testing for
FIV at the time of surgery or prior to surgery. Your cat probably doesn't
have it but it might be reassuring to be sure.
Mike Richards, DVM
Gingivitis plus
Q: Dear Dr Mike, As a cat breeder of many years,
I have in the past three years come across at least three of the kittens
I have bred suffering from Gingivitis, and some times ulcers on the tonge
and in the mouth, accompanied by 'smelly breath'. I realise that this may
be genetic in 'one' of my breeding lines, but do you know of an effective
treatment that would lead to a cure, rather than courses of antibiotics
when the ailment occurs? My cats have a good balanced diet, and do chew
on bones as well as 'some' dry foods. However this problem still comes
back, particuarly in the kitten stages, and up to one or two years old.
I would be grateful for your advice.
A: You didn't mention the breed of your
cats. There is a congenital problem with gingivitis in Abyssinians and
Persians in which there is significant overgrowth of the gingiva, resulting
in gingivitis. This condition is reported to resolve spontaneously as the
cats mature. We have found it necessary to treat the affected cats, using
repeated dental cleanings and sometimes removal of the excessive gingival
tissue prior to the time that the condition resolved. I think that this
is commonly the case. Siamese cats are reported to be prone to "trench
mouth" or ulceromembranous stomatitis. Same basic treatment plan except
that antibiotics are necessary to control this and it may clear up and
stay away. (from the Clinics of North America, Feline Infectious Diseases,
May 1993, Hoskins and Loar).
There are a number of causes of gingivitis in these and other cat breeds.
The causes get a lot more difficult to evaluate and the treatments a lot
less likely to work consistently with these other conditions, though.
Viral diseases play a major role in many cases of gingivitis in cats.
At least two viruses, feline immunodeficiency virus (FIV) and feline calicivirus
are capable of inciting or exacerbating gingivitis in cats. It is possible
that feline leukemia virus (FeLV) may also be involved in some cases of
gingivitis. Both of these viruses are common in cats. It is unclear whether
or not calicivirus is a primary cause of gingivitis or whether it just
causes problems in cats that are already immune compromised for some reason,
including FIV infection. In any case, these are difficult problems to control
since anti-viral medications tend to be only partially effective, at best.
Good control of all other factors contributing to the problem seems to
work best -- so again, dental prophylaxis, antibiotics to control secondary
infections if necessary and good nutrition and husbandry are all necessary.
There is a condition known as plasmacytic-lymphocytic gingivitis (sometimes
with stomatitis appended, too). It is an inflammatory condition affecting
the gingival tissues. This is an abnormal immune response that some people
feel is a form of allergy response in cats and others feel is another immune
system disorder. As far as I know, the exact cause of this problem has
not been worked out. It is diagnosed with biopsy specimens from the affected
gum tissue, usually after FIV and FeLV testing have been done to rule out
those problems. If there is no viral illness, treatment is usually attempted
using corticosteroids to suppress the immune system. They are probably
the most consistently effective medications. Other medications, including
gold salts and megestrol acetate have been used to treat this problem,
as well. A fairly common recommendation is to remove all of the teeth except
the four big canine teeth and the incisor teeth between them. This works
pretty well and most cats do fine without the teeth, even eating dry foods
readily. Alternatively, aggressive prophylaxis to prevent any dental disease,
treatment with immunosuppressive medications and quick treatment of any
secondary problems may provide good control of this problem.
There are several other possible causes of gingivitis in cats. The best
bet, if possible, is to have a biopsy done of the affected gingival tissue
and try to get to a diagnosis. It may be a good idea to screen for FIV
and FeLV virus in your cattery if you have not done that. Your vet can
help you figure out what is going on, perhaps with a little persistence
on everyone's part, since it can take a couple of tries at biopsies to
get a good answer.
Mike Richards, DVM
Last edited 09/23/02
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