Please note: The information on our
site is for everyone to read.
Please use it as often as you like.
However, Ask Dr Mike is available only to subscribers
of our Vetinfo Digest.
Please do not send questions if you are
not a subscriber.
Please use the search engine or one of the indexes
to see if the information
you need is already online. Please see Subscriber
info for details.
Subscriber
Info
The income from the subscriptions helps defray the
cost of maintaining the site and allows us to keep the large amount of information on www.vetinfo.com
free to our readers.
Feline Leukemia Test
Feline leukemia
testing accuracy
Saliva
tests
Feline Leukemia test
also see Feline Leukemia
also see Feline Leukemia Treatments
also see Feline leukemia Medication
also see Living Arrangement Problems
also see FIP - Feline Infectious Peritonitis
also see FIV - Feline Immunodeficiency Virus
also see Infectious Disease
also see Vaccine related Problems
also see Zoonotic Disease
Feline
Leukemia - testing accuracy
Q: Dear Dr Richards
I breed Bengal cats. My tom has been tested as has the other
animals that he
lives with. My Queens are all healthy and live completely isolated
indoors.
I have had two people that have purchased kittens from me say that
their
kittens have tested positive for fel leuk. One was 2 years ago,
and the
other is recent. Can you explain the limitations of the tests
that are done?
Is it possible that these are falible and that the cats are not in
danger or
dangerous. The cat that was diagnosed 2 years ago lives with
other cats, and
has not infected anyone either. They are all vaccinated yearly.
What is
happening?
M
A: M-
There are a number of possible explanations for the situation you are
encountering.
The screening tests used for feline leukemia in the office in veterinary
practices do have a small percentage of false positive results. The
exact
percentages vary from test to test but they are probably between 1
and 5%.
Since a lot of cats will be tested who won't have the disease and only
a
small number of cats will be tested who do have the disease it becomes
somewhat likely that a test that is positive is inaccurate. All cats
should
be tested at least twice when they show up positive on feline leukemia
testing.
The other problem is that cats can be negative on a test for feline
leukemia and then become positive due to recurrence of a suppressed
infection, a new infection or because of a false negative result to
begin
with. False negative tests are supposed to be less common than false
positives, though.
The current thinking is that most cats are infected with feline leukemia
virus when they are young, less than one year of age. This means that
there
is a chance that one of your cats is positive and you do not realize
it but
also a chance that the kittens contacted the disease away from your
place
=== along with the chance of false positive tests.
If you can talk the kitten owners into retesting and then see what the
results are you might have a better idea of how much need there really
is
to retest your cats.
Mike Richards, DVM
Saliva
tests for feline leukemia virus infection
Q: Hi,
I would like to know if the saliva test for FeLV is good enought.
I heard of this test throug the internet. Please let me know if the
blood test is more reliable than this test..
Yury
A: Yury-
Sometimes information relating to testing procedures changes rapidly
and it is possible that there is new information that I am not aware of
but my current understanding of the saliva tests for feline leukemia virus
infection is that they are still plagued with both false positive and false
negative results to a much higher degree than the screening blood tests.
Mike Richards, DVM
Feline leukemia test
Q: About 2 1/2 months ago I lost a 3 year old cat
to feline leukemia. He was a cat that I rescued from a city pound when
he was about 6 weeks old. I took him to the vet about 2 weeks after I got
him and at that time I was told that he had feline leukemia. The Vet told
me that he could live a long time with that or a short time with it...his
was too short. Anyway on Saturday I purchased a Birman kitten and was told
that she was in good health...she had not been tested for feline leukemia
or FIP as both of her parents had tested negative. I took her to my own
vet on Tuesday and they tested her and vaccinated her...however they did
2 different tests on her as they said the first leukemia test showed a
faint positive so they did another test they said that tested for feline
leukemia and feline aids. They said this test was negative and that it
is more reliable than the first test they did. So why do they do the first
test if it is not very reliable. By the way, I had thrown out all of the
first cats things when I had to put him to sleep so she had new litter
box and feeding bowls, ect. Any thoughts on this?
A: I can't say why your vet uses two different
tests for feline leukemia. We keep two different tests for heartworm disease
specifically for retesting of positive results using a different testing
method, though. Usually on ambiguous feline leukemia tests we recommend
retesting in a month or so. In theory this should allow the cats who are
infected but whose immune systems will kill the virus to clear it from
their bloodstream. Cats early in an infection whose immune systems don't
win should get worse. The only problem is that some cats sequester the
virus out of their bloodstream, making the test negative even though they
are infected. There is no foolproof way to test for feline leukemia, yet.
Feline leukemia virus does not live long at all outside of the cat --
probably less than a few seconds. There should be no way your new kitten
can catch this disease from your previous cat. Throwing out the food bowls,
etc., was probably not necessary but being cautious isn't a bad idea.
Michael Richards, DVM