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Feline Leukemia Medication and Supplements

 N-acetylcysteine
 Feline leukemia medication
 
 

also see Feline leukemia
also see Feline Leukemia Test
also see Feline Leukemia Treatments
also see Living Arrangement Problems
also see FIP - Feline Infectious Peritonitis
also see FIV - Feline Immunodeficiency Virus
also see Infectious Disease
also see Vaccine related Problems
also see Zoonotic Disease

N-acetylcysteine

Question: I am interested in giving NAC as a supplement to a FeLV cat.  My vet is
uncertain about the amount to give and is concerned that an inappropriate dosage might prove too toxic.  Can you recommend an amount to give?  Many thanks.
Sincerely,
E. T-J.
 
 

Answer: E.-

I am assuming that you are referring to N-acetylcysteine, which has shown
some promise in studies in rats for reducing viral replication in feline
immunodeficiency virus infections ( Mortola, Okuda, et al, 1998). In the
same study it was noted to reduce apoptosis (cell death) which might not be
a good thing when used for feline leukemia virus infection rather than
feline immunodeficiency virus infection. In the case of FeLV, the virus may
lead to cancer and apoptosis is a good thing when it affects cancer cells.
That is just my own thinking -- not something I have seen about this use in
the literature.

I couldn't find a dose for use for FIV cats, but there is a dosage for use
of N-Acetylcysteine at 140 mg/kg initially, followed by 70 mg/kg every 4
hrs, given orally or intravenously for acetaminophen toxicity that has been
published. Usually this is given for a few days (3 to 5) until the cat
recovers, so I don't know if it would have to be adjusted further for long
term use.

Mike Richards, DVM
12/10/99
 
 

Feline leukemia - Medication

Q: hi,
I'm wondering if i should be putting my 7 year old FeLV male cat on
any of the new drugs prescribed for FeLV? My cat tested positive twice
four years ago when we took him in as a stray. We spoil our fat cat
(approx. 15lbs) and love him to death...Outwardly he appears
symptomless,however, he has had blood work that showed he has persistant
viremia (not sure if spelled correctly)..very low white blood cells.
Our cat doesn't take well to any medications especially antibiotics,
we've tried numerous ones and they make him depressed and he'll stop
eating etcc.. it's weird.

Anyhow any info. you could provide would be helpfull..thank You!

karen

A: Karen-

I am not aware of a new highly effective medication for feline leukemia. If
you know the medication name I will be glad to research it.

Mike Richards, DVM
 

 Last edited 04/20/04

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